Developmental toxicity of prenatal exposure to toluene
نویسندگان
چکیده
منابع مشابه
Bisphenol A: developmental toxicity from early prenatal exposure.
Bisphenol A (BPA) exposure has been documented in pregnant women, but consequences for development are not yet widely studied in human populations. This review presents research on the consequences for offspring of BPA exposure during pregnancy. Extensive work in laboratory rodents has evaluated survival and growth of the conceptus, interference with embryonic programs of development, morpholog...
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متن کاملReproductive and developmental toxicity studies of toluene. I. Teratogenicity study of inhalation exposure in pregnant rats.
Toluene is a widely used solvent in industry which is the subject of abuse among the younger generation. A teratogenicity study of toluene by inhalation exposure was carried out in Sprague-Dawley rats and the effects on dams, fetuses and offspring were assessed. Pregnant females were exposed to 600 or 2000 ppm toluene for 6 h/day from day 7 to day 17 of pregnancy. The control group inhaled cond...
متن کاملReproductive and developmental toxicity of toluene: a review.
Toluene is a widely used industrial solvent, and humans may also have high exposures to toluene from the deliberate inhalation ("sniffing") of paint reducer, paint thinner, or paint for their narcotic effects. A number of case reports describe neonatal effects that have been attributed to toluene abuse during pregnancy. These effects may include intrauterine growth retardation, premature delive...
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The polydrug pattern of drug use by pregnant women, combined with the varying purity, dosage, and timing during pregnancy when drugs are taken, makes it very difficult to determine the developmental impact of any specific drug. Nevertheless, studies of drug-exposed newborns suggest an array of behavioral characteristics that make their care challenging, and a few studies indicate that some pren...
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ژورنال
عنوان ژورنال: The AAPS Journal
سال: 2006
ISSN: 1550-7416
DOI: 10.1007/bf02854915